HTLV‐1 cell‐free DNA in plasma as a potential biomarker in HTLV‐1 carriers and adult T‐cell leukemia‐lymphoma
نویسندگان
چکیده
Viral cell-free DNA (cfDNA) in plasma has been widely evaluated for detecting cancer and monitoring disease virus-associated tumors. We investigated whether the amount of cfDNA human T-cell leukemia virus type 1 (HTLV-1) correlates with state adult leukemia-lymphoma (ATL). HTLV-1 aggressive ATL was significantly higher than that indolent asymptomatic carriers. Notably, patients lymphoma represented chronic smoldering subtypes, though they had no abnormal lymphocytes peripheral blood. can be a universal biomarker reflects expansion clones.
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ژورنال
عنوان ژورنال: EJHaem
سال: 2023
ISSN: ['2688-6146']
DOI: https://doi.org/10.1002/jha2.725